Centro de Química

Professor Associado

Maria José Alves

Maria José Chão Alves

Grau Académico

Doutoramento

Cargo Atual

Professor Associado

mja@quimica.uminho.pt

Publicações

62

H-index

Estudantes PhD

4

Projetos

3

Publicações

Artigo

Golgi α-mannosidase: opposing structures of Drosophila melanogaster and novel human model using molecular dynamics simulations and docking at different pHs

Artem Drogalin; Luís S. Monteiro; Maria José Alves; Tarsila G. Castro

Journal of Biomolecular Structure and Dynamics , 2023

Artigo

Synthesis of novel sugar derived aziridines, as starting materials giving access to sugar amino acid derivatives

Cristina E. A. Sousa; Maria J. Alves

Amino Acids , 2021

Artigo

(3S,4R)-3,4-Dihydroxy-N-alkyl-l-homoprolines: synthesis and computational mechanistic studies

David S. Freitas; Cristina E. A. Sousa; Joana Parente; Artem Drogalin; António Gil Fortes; Nuno M. F. S. A. Cerqueira; Maria J. Alves

Organic & Biomolecular Chemistry , 2019

Artigo

A Short Synthesis of (2S,3S,4R)-Dihydroxyhomoprolines from d-Erythrose-Derived 5,6-Dihydro-2H-pyran-2-one

Synthesis , 2019

Artigo

Synthesis and Bioactivity of New Analogue of Bicyclic 1-Azafagomine

Akhundova, Fidan N.; Kurbanova, Malahat M.; Huseynzada, Alakbar E.; Alves, Maria J.; Sujayev, Afsun R.

ChemistrySelect , 2019

Artigo

Total Stereoselective Michael Addition of N- and S- Nucleophiles to a d-Erythrosyl 1,5-Lactone Derivative. Experimental and Theoretical Studies Devoted to the Synthesis of 2,6-Dideoxy-4-functionalized-d-ribono-hexono-1,4-lactone

Juliana F. Rocha; David S. Freitas; Jennifer Noro; Carla S. Silva Teixeira; Cristina E. A. Sousa; Maria J. Alves; Nuno M. F. S. A. Cerqueira

The Journal of Organic Chemistry , 2018

Artigo

Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates

Babar, Ayesha; Yar, Muhammad; Tarazi, Hamadeh; Duarte, Vera; Alshammari, Mohammed B.; Gilani, Mazhar Amjad; Iqbal, Haffsah; et al.

Med. Chem. Res. , 2017

Artigo

Total Facial Discrimination of 1,3-Dipolar Cycloadditions in a d-Erythrose 1,3-Dioxane Template: Computational Studies of a Concerted Mechanism

Cristina E. A. Sousa; António M. P. Ribeiro; António Gil Fortes; Nuno M. F. S. A. Cerqueira; Maria J. Alves

The Journal of Organic Chemistry , 2017

Artigo

Exploiting the Antiparasitic Activity of Naphthalimides Derivatives

Alves, Maria

Int. J. Chem. Pharm. Sci , 2016

Artigo

Styrene epoxidation over heterogeneous manganese(III) complexes

Kuniarska-Biernacka, I.; Lisinska-Czekaj, A.; Czekaj, D.; José Alves, M.; Mauricio Fonseca, A.; Correia Neves, I.

Arch. Metall. Mater. , 2016

Artigo

Total Facial Selectivity of a D-Erythrosyl Aromatic Imine in [4p+2p] Cycloadditions; Synthesis of 2-Alkylpolyol 1,2,3,4-Tetrahydroquinolines

Organic & Biomolecular Chemistry , 2016

Artigo

Evaluation of New Naphthalimides as Potential Anticancer Agents against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT- 15 Cell Lines

J, Noro; J, Maciel

Organic Chemistry: Current Research , 2015

Artigo

Enantioselective Diels-Alder Cycloadditions in the Synthesis of Two Enantiomeric Sets of Chiral Polihydroxylated Pipecolic Acid Derivatives

Synlett , 2014

Artigo

Norbornene oxidation by chiral complexes encapsulated in NaY zeolite

Kuźniarska-Biernacka, I.; Parpot, P.; Oliveira, C.; Silva, A.R.; Alves, M.J.; Fonseca, A.M.; Neves, I.C.

Journal of Physical Chemistry C , 2014

Artigo

Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as a- and ß-glucosidase inhibitors

Riaz, Sadaf; Khan, Islam Ullah; Yar, Muhammad; Ashraf, Muhammad; Rehman, Tanzeel Ur; Shaukat, Ayesha; Jamal, Syed Babar; Duarte, Vera C.M.; Alves, Maria J.

Bioorganic Chemistry , 2014

Artigo

Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as alpha- and beta-glucosidase inhibitors

Bioorg. Chem. , 2014

Artigo

Synthesis and evaluation of α-, β-glucosidase inhibition of 1-N-carboxamide-1-azafagomines and 5-epi-1-azafagomines

Mendes, R.; Duarte, V.C.M.; Gil Fortes, A.; Alves, M.J.

Carbohydrate Research , 2014

Artigo

Synthesis of Iminosugars from tetroses

Sousa, C.E.; Mendes, R.R.; Costa, F.T.; Duarte, V.C.M.; Fortes, A.G.; Alves, M.J.

Curr. Org. Synth. , 2014

Artigo

Asymmetric Diels-Alder cycloadditions of d-erythrose 1,3-butadienes to achiral t-butyl 2H-azirine 3-carboxylate

Duarte, V.C.M.; Faustino, H.; Alves, M.J.; Gil Fortes, A.; Micaelo, N.

Tetrahedron Asymmetry , 2013

Artigo

Highly stereoselective cycloadditions of Danishefsky's diene to (-)-8-phenylmenthyl and (+)-8-phenylneomenthyl glyoxylate N-phenylethylimines

García-Mera, X.; Alves, M.J.; Goth, A.; Do Vale, M.L.; Rodríguez-Borges, J.E.

Tetrahedron , 2013

Ver mais

Equipa

Maria José Alves

ORCID

CIÊNCIA VITAE

SCOPUS ID

Publicações

62

H-index

Estudantes PhD

4

Projetos

3

Publicações

Golgi α-mannosidase: opposing structures of Drosophila melanogaster and novel human model using molecular dynamics simulations and docking at different pHs

Synthesis of novel sugar derived aziridines, as starting materials giving access to sugar amino acid derivatives

(3S,4R)-3,4-Dihydroxy-N-alkyl-l-homoprolines: synthesis and computational mechanistic studies

A Short Synthesis of (2S,3S,4R)-Dihydroxyhomoprolines from d-Erythrose-Derived 5,6-Dihydro-2H-pyran-2-one

Synthesis and Bioactivity of New Analogue of Bicyclic 1-Azafagomine

Total Stereoselective Michael Addition of N- and S- Nucleophiles to a d-Erythrosyl 1,5-Lactone Derivative. Experimental and Theoretical Studies Devoted to the Synthesis of 2,6-Dideoxy-4-functionalized-d-ribono-hexono-1,4-lactone

Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates

Total Facial Discrimination of 1,3-Dipolar Cycloadditions in a d-Erythrose 1,3-Dioxane Template: Computational Studies of a Concerted Mechanism

Exploiting the Antiparasitic Activity of Naphthalimides Derivatives

Styrene epoxidation over heterogeneous manganese(III) complexes

Total Facial Selectivity of a D-Erythrosyl Aromatic Imine in [4p+2p] Cycloadditions; Synthesis of 2-Alkylpolyol 1,2,3,4-Tetrahydroquinolines

Evaluation of New Naphthalimides as Potential Anticancer Agents against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT- 15 Cell Lines

Enantioselective Diels-Alder Cycloadditions in the Synthesis of Two Enantiomeric Sets of Chiral Polihydroxylated Pipecolic Acid Derivatives

Norbornene oxidation by chiral complexes encapsulated in NaY zeolite

Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as a- and ß-glucosidase inhibitors

Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as alpha- and beta-glucosidase inhibitors

Synthesis and evaluation of α-, β-glucosidase inhibition of 1-N-carboxamide-1-azafagomines and 5-epi-1-azafagomines

Synthesis of Iminosugars from tetroses

Asymmetric Diels-Alder cycloadditions of d-erythrose 1,3-butadienes to achiral t-butyl 2H-azirine 3-carboxylate

Highly stereoselective cycloadditions of Danishefsky's diene to (-)-8-phenylmenthyl and (+)-8-phenylneomenthyl glyoxylate N-phenylethylimines

Projetos

Estratégias Concisas e Estereoseletivas de Síntese de Aza-açúcares. Estudos Teóricos e Biológicos dos Produtos

Estratégia Comum de Síntese de Aza-açúcares e Nucleósidos Modificados. Avaliação Biológica dos Produtos

Síntese e Reactividade de 2H-Azirinas Electrofílicas

Estudantes PhD

Artem Drogalin

Cristina Elisabete Araújo de Sousa

Nuno Gonçalo Azoia Lopes

João Henriques de Sousa