Centro de Química

Publicações

Artigo

Tunable Spun Fiber Constructs in Biomedicine: Influence of Processing Parameters in the Fibers’ Architecture

Catarina S. Miranda; Ana Francisca G. Silva; Sílvia M. M. A. Pereira-Lima; Susana P. G. Costa; Natália C. Homem; Helena P. Felgueiras

Pharmaceutics , 2022

Artigo em Ata

Synthesis of Peptaibolin, an Antimicrobial Peptide

Ana R. M. Ribeiro; Helena P. Felgueiras; Susana P. G. Costa; Sílvia M. M. A. Pereira-Lima; Ana R. M. Ribeiro; Helena P. Felgueiras; Susana P. G. Costa; Sílvia M. M. A. Pereira-Lima

2020

Artigo em Ata

Industrial engineering and management PBL implementation: An effortless experience?

Alves, A.C.; Moreira, F.; Leão, C.P.; Pereira, A.C.; Pereira-Lima, S.M.M.A.; Malheiro, M.T.; Lopes, S.O.; Oliveira, S.; Alves, A.C.; Moreira, F.; Leão, C.P.; Pereira, A.C.; Pereira-Lima, S.M.M.A.; Malheiro, M.T.; Lopes, S.O.; Oliveira, S.

International Symposium on Project Approaches in Engineering Education , 2019

Artigo

Peptaibolin analogues by incorporation of α,α-dialkylglycines: Synthesis and study of their membrane permeating ability

Castro, V.I.B.; Carvalho, C.M.; Fernandes, R.D.V.; Pereira-Lima, S.M.M.A.; Castanheira, E.M.S.; Costa, S.P.G.

Tetrahedron , 2016

Artigo

Synthesis of dehydrodipeptide and N-ethyl-dehydrodipeptide derivatives with an α-aminoisobutyric acid residue

Monteiro, L.S.; Pereira-Lima, S.M.; Pereira, S.; Monteiro, L.S.; Pereira-Lima, S.M.; Pereira, S.

Current Chemical Biology , 2014

Artigo

Synthesis of N-alkyl-C^α,α-dimethylglycine derivatives

Monteiro, L.S.; Pereira-Lima, S.M.M.A.; Pereira, S.; Machado, J.N.; Monteiro, L.S.; Pereira-Lima, S.M.M.A.; Pereira, S.; Machado, J.N.

Arkivoc , 2014

Artigo

α,α-Dialkylglycines obtained by solid phase Ugi reaction performed over isocyanide functionalized resins

Aguiam, N.R.; Castro, V.I.; Ribeiro, A.I.F.; Fernandes, R.D.V.; Carvalho, C.M.; Costa, S.P.G.; Pereira-Lima, S.M.M.A.

Tetrahedron , 2013

Artigo

Straightforward, racemization-free synthesis of peptides with fairly to very bulky di- and trisubstituted glycines

Pinto, F.C.S.C.; Pereira-Lima, S.M.M.A.; Maia, H.L.S.; Pinto, F.C.S.C.; Pereira-Lima, S.M.M.A.; Maia, H.L.S.

Tetrahedron , 2009

Artigo

Synthesis and kinetic investigation of the selective acidolysis of para-substituted N-benzyl- or N-phenyl-N-phenylacetyl-α,α-dialkylglycine cyclohexylamides

Pinto, F.C.S.C.; Pereira-Lima, S.M.M.A.; Ventura, C.; Albuquerque, L.; Gonçalves-Maia, R.; Maia, H.L.S.; Pinto, F.C.S.C.; Pereira-Lima, S.M.M.A.; Ventura, C.; Albuquerque, L.; Gonçalves-Maia, R.; Maia, H.L.S.

Tetrahedron , 2006

Artigo

Kinetic investigation of the effect of the amino acid side chains in the selective acidolysis of N-acyl-N,α,α-trialkyl glycine amides

Jiang, W.-Q.; Pereira-Lima, S.M.M.A.; Ventura, C.; Costa, S.P.G.; Albuquerque, L.; Gonçalves-Maia, R.; Maia, H.L.S.; Jiang, W.-Q.; Pereira-Lima, S.M.M.A.; Ventura, C.; Costa, S.P.G.; Albuquerque, L.; Gonçalves-Maia, R.; Maia, H.L.S.

Journal of Peptide Science , 2005

Artigo

An improved approach for the synthesis of α,α-dialkyl glycine derivatives by the Ugi-Passerini reaction

Costa, S.P.G.; Maia, H.L.S.; Pereira-Lima, S.M.M.A.; Costa, S.P.G.; Maia, H.L.S.; Pereira-Lima, S.M.M.A.

Organic and Biomolecular Chemistry , 2003

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Silvia Manuela Lima

ORCID

CIÊNCIA VITAE

SCOPUS ID

Publicações

11

H-index

Estudantes PhD

0

Projetos

4

Publicações

Tunable Spun Fiber Constructs in Biomedicine: Influence of Processing Parameters in the Fibers’ Architecture

Synthesis of Peptaibolin, an Antimicrobial Peptide

Industrial engineering and management PBL implementation: An effortless experience?

Peptaibolin analogues by incorporation of α,α-dialkylglycines: Synthesis and study of their membrane permeating ability

Synthesis of dehydrodipeptide and N-ethyl-dehydrodipeptide derivatives with an α-aminoisobutyric acid residue

Synthesis of N-alkyl-C^α,α-dimethylglycine derivatives

α,α-Dialkylglycines obtained by solid phase Ugi reaction performed over isocyanide functionalized resins

Straightforward, racemization-free synthesis of peptides with fairly to very bulky di- and trisubstituted glycines

Synthesis and kinetic investigation of the selective acidolysis of para-substituted N-benzyl- or N-phenyl-N-phenylacetyl-α,α-dialkylglycine cyclohexylamides

Kinetic investigation of the effect of the amino acid side chains in the selective acidolysis of N-acyl-N,α,α-trialkyl glycine amides

An improved approach for the synthesis of α,α-dialkyl glycine derivatives by the Ugi-Passerini reaction

Projetos

Desenho baseado na estrutura, atividade biológica e estudos de permeação de membrana modelo de peptaibols antimicrobianos com aminoácidos não naturais

Investigação de modificações miméticas de péptidos bioativos por inclusão de aminoácidos sintéticos

Péptido CW49 como potencial agente antimicrobiano contra as bactérias colonizadoras mais prevalentes em úlceras do pé diabético

Filmes nanofibrosos eletrofiados sensíveis a pH e modificados com o péptido WAAPV inibem a ação de bactérias e de enzimas proteolíticas em úlceras do pé diabético.

Estudantes PhD

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Contactos

Equipa

Silvia Manuela Lima

ORCID

CIÊNCIA VITAE

SCOPUS ID

Publicações

11

H-index

Estudantes PhD

0

Projetos

4

Publicações

Tunable Spun Fiber Constructs in Biomedicine: Influence of Processing Parameters in the Fibers’ Architecture

Synthesis of Peptaibolin, an Antimicrobial Peptide

Industrial engineering and management PBL implementation: An effortless experience?

Peptaibolin analogues by incorporation of α,α-dialkylglycines: Synthesis and study of their membrane permeating ability

Synthesis of dehydrodipeptide and N-ethyl-dehydrodipeptide derivatives with an α-aminoisobutyric acid residue

Synthesis of N-alkyl-Cα,α-dimethylglycine derivatives

α,α-Dialkylglycines obtained by solid phase Ugi reaction performed over isocyanide functionalized resins

Straightforward, racemization-free synthesis of peptides with fairly to very bulky di- and trisubstituted glycines

Synthesis and kinetic investigation of the selective acidolysis of para-substituted N-benzyl- or N-phenyl-N-phenylacetyl-α,α-dialkylglycine cyclohexylamides

Kinetic investigation of the effect of the amino acid side chains in the selective acidolysis of N-acyl-N,α,α-trialkyl glycine amides

An improved approach for the synthesis of α,α-dialkyl glycine derivatives by the Ugi-Passerini reaction

Projetos

Desenho baseado na estrutura, atividade biológica e estudos de permeação de membrana modelo de peptaibols antimicrobianos com aminoácidos não naturais

Investigação de modificações miméticas de péptidos bioativos por inclusão de aminoácidos sintéticos

Péptido CW49 como potencial agente antimicrobiano contra as bactérias colonizadoras mais prevalentes em úlceras do pé diabético

Filmes nanofibrosos eletrofiados sensíveis a pH e modificados com o péptido WAAPV inibem a ação de bactérias e de enzimas proteolíticas em úlceras do pé diabético.

Estudantes PhD

Synthesis of N-alkyl-C^α,α-dimethylglycine derivatives